The medication cinacalcet may also be used to decrease PTH levels in those unable to have surgery although it is not a cure. In those without symptoms, mildly increased blood calcium levels, normal kidneys, and normal bone density monitoring may be all that is required. Primary hyperparathyroidism may only be cured by removing the adenoma or overactive parathyroid glands. The diagnosis of primary hyperparathyroidism is made by finding elevated calcium and PTH in the blood. Secondary hyperparathyroidism typically occurs due to vitamin D deficiency, chronic kidney disease, or other causes of low blood calcium. Very rarely it may be due to parathyroid cancer. Most of the remainder are due to several of these adenomas. In 80% of cases, primary hyperparathyroidism is due to a single benign tumor known as a parathyroid adenoma. Both primary and secondary may result in osteoporosis (weakening of the bones). Other symptoms may include bone pain, weakness, depression, confusion, and increased urination. With long-standing hyperparathyroidism, the most common symptom is kidney stones. In healthy people, when blood calcium levels are high, parathyroid hormone levels should be low. Symptoms of hyperparathyroidism are caused by inappropriately normal or elevated blood calcium leaving the bones and flowing into the blood stream in response to increased production of parathyroid hormone. This occurs from a disorder either within the parathyroid glands ( primary hyperparathyroidism) or as response to external stimuli ( secondary hyperparathyroidism). Hyperparathyroidism is an increase in parathyroid hormone (PTH) levels in the blood. Monitoring, surgery, intravenous normal saline, cinacalcet Secondary: vitamin D deficiency, chronic kidney disease, low blood calcium Primary: parathyroid adenoma, multiple benign tumors, parathyroid cancer None, kidney stones, weakness, depression, bone pains, confusion, increased urination
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